American Skullcap is a perennial herb from the mint family effective in relieving anxiety and seizures. It contains two important flavonoids, baicalin and wogonin. These compounds are thought to bind to GABA receptors in the brain, providing sedative and anxiety-reducing effects.

RELORA® combines extracts from Magnolia officinalis and Phellodendron amurense barks, known for their traditional use in supporting overall health. This blend helps maintain calm and balanced moods in pets. Magnolia’s honokiol and Phellodendron’s berberine work together to support stress management. RELORA® provides a natural approach to help pets cope with everyday stressors.

Passionflower has been shown in studies to reduce anxiety in animals. Passionflower works by increasing gamma amino butyric acid (GABA) levels in the brain, a neurotransmitter that promotes relaxation and reduces tension. Passionflower offers these calming benefits without adverse side effects.

Known for its calming effects, it helps alleviate stress and improve sleep quality. The active compounds, such as valepotriate and valeric acid, are believed to increase GABA production in the brain, which helps reduce stress and promote relaxation. Valerian root’s natural constituents work to down-regulate stress hormones in the brain’s amygdala, contributing to its calming and sedative properties.

Lemon Balm is used to aid digestion and soothe nervous disturbances during sleep. Studies show it can improve mood, memory, and cognitive function, as well as alleviate anxiety and depressive symptoms. The key compound, rosmarinic acid, helps maintain optimal GABA levels in the brain by inhibiting GABA transaminase, contributing to Lemon Balm’s calming effects.

Peaceful Pet utilizes RELISSA®, a phytosome complex from Indena S.p.A., ensuring optimal bioavailability of rosmarinic acid and hydroxycinnamic acid for peak therapeutic benefits. Indena S.p.A. is renowned for producing high-quality plant-derived active ingredients.

L-theanine, an amino acid found in green tea, helps relieve stress, improve mood, and maintain normal sleep patterns. Animal studies show L-theanine reduces anxiety and depression by increasing brain-derived neurotrophic factor (BDNF) in the hippocampus. BDNF supports the growth and maintenance of nerve cells. L-theanine also supports positive emotions and mood.

Vitamin B6, in its bioactive form pyridoxal 5’-phosphate, is essential to support positive emotions and mood. Vitamin B6 promotes neurotransmitter synthesis. These neurotransmitters help nerve cells communicate, regulate appetite, and maintain a positive mood. A deficiency in vitamin B6 can disrupt these processes, leading to behavioral issues in pets. ThorneVet’s Peaceful Pet includes this vital nutrient to support balanced neurotransmitter production and overall nervous system health.