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Vitamin B1 (Thiamin HCl)

PRIMARY FUNCTION

Essential water-soluble vitamin supporting energy metabolism, nervous system health, and normal growth in dogs and cats.

HOW IT SUPPORTS PET HEALTH

Vitamin B1, also known as thiamin or thiamine hydrochloride (HCl), plays a critical role in carbohydrate metabolism and the generation of cellular energy (ATP). It is required for the proper functioning of the nervous system, maintenance of normal growth, and the synthesis of neurotransmitters such as acetylcholine. Thiamine is especially important for active tissues like the brain and heart, making it vital for overall vitality and neurological health in both dogs and cats[1][3][6].

FUNCTIONAL OVERVIEW

Thiamine acts as a coenzyme in several key metabolic pathways, including the breakdown of glucose for energy production. It supports:

  • Energy Metabolism: Facilitates the conversion of carbohydrates into usable energy.
  • Nervous System Health: Essential for nerve impulse transmission and neurotransmitter synthesis.
  • Normal Growth and Appetite: Supports healthy development and appetite regulation.

Because thiamine is water-soluble and not stored in large quantities in the body, it must be supplied regularly through the diet[1][3][6].

COMMON VETERINARY USES
Species Studied
  • Dogs
  • Cats
Primary Benefits for Pets
  • Prevents Deficiency: Ensures healthy nerve and muscle function, and prevents neurological disorders.
  • Supports Metabolism: Enables efficient energy production from carbohydrates.
  • Promotes Growth and Appetite: Maintains normal growth, appetite, and body condition.
Veterinary Use Cases
  • Treating and preventing thiamine deficiency, especially in pets on unbalanced or unconventional diets.
  • Supporting recovery from gastrointestinal disease, malabsorption, or chronic illness.
  • Adjunctive therapy in cases of lead poisoning or ethylene glycol toxicity.
CONTRAINDICATIONS & SENSITIVITIES

Thiamine is generally very safe and well tolerated. Side effects are rare, but hypersensitivity reactions can occur in some animals. Because it is water-soluble, excess amounts are excreted in urine, minimizing the risk of toxicity[1][3].

INGREDIENT SOURCING & QUALITY STANDARDS

Thiamine HCl used in pet supplements is synthesized to high purity standards and is readily absorbed when administered orally or by injection. Pet foods and supplements are formulated to meet the specific thiamine requirements of dogs and cats, as established by the NRC and AAFCO[6].

RESEARCH AT A GLANCE
  1. Role in Energy and Nerve Health: Thiamine is vital for carbohydrate metabolism, nerve impulse transmission, and acetylcholine synthesis in dogs and cats. URL: https://www.petplace.com/article/drug-library/drug-library/library/thiamine-vitamin-b1-for-dogs-and-cats
  2. Deficiency Risks and Clinical Signs: Prolonged thiamine deficiency can cause neurological and systemic symptoms, and may be fatal if not reversed. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC5753639/
  3. Dietary Requirements and Food Sources: Dogs and cats depend on dietary thiamine, and unconventional or unbalanced diets increase the risk of deficiency. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC7840196/
TRADITIONAL APPLICATIONS

Thiamine-rich foods such as whole grains, pork, and organ meats have long been valued for supporting energy, appetite, and neurological health in both humans and animals.

DISCLAIMER

This ingredient overview is intended for educational purposes only and should not be considered veterinary advice. Always consult with your veterinarian before introducing new supplements or making changes to your pet’s healthcare regimen.