PRIMARY FUNCTION
Natural calming agent for stress relief, anxiety reduction, and cortisol management.
HOW IT SUPPORTS PET HEALTH
Phellodendron amurense, a key component of the proprietary blend RELORA®, is derived from the bark of the Phellodendron tree. It is known for its anxiolytic and stress-reducing properties. Combined with *Magnolia officinalis*, RELORA® enhances relaxation, moderates stress-related behaviors, and supports healthy cortisol levels. Phellodendron bark contains bioactive compounds like berberine, which has been shown to regulate stress responses and promote emotional balance in pets. This makes it particularly beneficial for dogs and cats experiencing chronic stress or anxiety.
FUNCTIONAL OVERVIEW
The active compounds in *Phellodendron amurense*, particularly berberine, help regulate cortisol production and reduce excitability in the central nervous system. Berberine also has neuroprotective properties that support overall nervous system health. RELORA®, standardized to honokiol (from *Magnolia officinalis*) and berberine (from *Phellodendron*), provides synergistic effects that enhance its calming properties while supporting mood balance in pets.
COMMON VETERINARY USES
Species Studied
- Dogs
- Cats
Primary Benefits for Pets
- Anxiety Relief: Reduces acute and chronic stress responses.
- Cortisol Regulation: Helps maintain healthy cortisol levels during stress.
- Nervous System Support: Promotes relaxation without sedation.
- Mood Enhancement: Improves emotional balance and reduces tension.
Veterinary Use Cases
- Managing separation anxiety or noise phobias in dogs.
- Supporting calmness during veterinary visits or travel.
- Reducing stress-related behaviors in cats, such as excessive grooming or vocalization.
- Promoting relaxation in pets with chronic anxiety or hyperactivity.
CONTRAINDICATIONS & SENSITIVITIES
RELORA® is generally safe when used at appropriate doses. However, it should be used cautiously in pets with low blood pressure or those taking sedatives or other medications affecting the central nervous system. Rare side effects include mild digestive upset or drowsiness. Always consult your veterinarian before use.
INGREDIENT SOURCING & QUALITY STANDARDS
RELORA® is a proprietary blend of *Magnolia officinalis* and *Phellodendron amurense* bark extracts standardized to honokiol and berberine content. The ingredients are rigorously tested for purity and potency to ensure consistent efficacy and safety for pets.
RESEARCH AT A GLANCE
- Anxiolytic Effects on Animals: Studies demonstrate that berberine from Phellodendron bark has significant anxiolytic activity in animal models, reducing stress-related behaviors without sedative side effects. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC3750820/
- Cortisol Regulation in Pets: Research indicates that RELORA®, combining Magnolia and Phellodendron extracts, effectively reduces cortisol exposure and improves mood state parameters in stressed animals. URL: https://www.springermedizin.de/effect-of-magnolia-officinalis-and-phellodendron-amurense-relora/9593872
- Nervous System Support for Dogs and Cats: Studies highlight the ability of Phellodendron to promote relaxation by modulating neurotransmitter activity, making it effective for managing anxiety in pets. URL: https://www.petmd.com/dog/behavior/dog-calming-products-help-ease-dog-anxiety
TRADITIONAL APPLICATIONS
Historically, *Phellodendron amurense* has been used in traditional Chinese medicine as an adaptogen to manage stress, improve mood, and support gastrointestinal health. Modern veterinary applications have adapted these uses to address stress-related behaviors and promote relaxation in pets.
DISCLAIMER
This ingredient overview is intended for educational purposes only and should not be considered veterinary advice. Always consult with your veterinarian before introducing new supplements or making changes to your pet’s healthcare regimen.
